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anlotinib alters tumor immune microenvironment by downregulating PD-L1 expression on vascular endoth...

anlotinib alters tumor immune microenvironment by downregulating PD-L1 expression on vascular endoth...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7198575

anlotinib alters tumor immune microenvironment by downregulating PD-L1 expression on vascular endothelial cells

About this item

Full title

anlotinib alters tumor immune microenvironment by downregulating PD-L1 expression on vascular endothelial cells

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2020-05, Vol.11 (5), p.309, Article 309

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Aberrant vascular network is a hallmark of cancer. However, the role of vascular endothelial cells (VECs)-expressing PD-L1 in tumor immune microenvironment and antiangiogenic therapy remains unclear. In this study, we used the specimens of cancer patients for immunohistochemical staining to observe the number of PD-L1
+
CD34
+
VECs and...

Alternative Titles

Full title

anlotinib alters tumor immune microenvironment by downregulating PD-L1 expression on vascular endothelial cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7198575

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7198575

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-020-2511-3

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