PKCθ-JunB axis via upregulation of VEGFR3 expression mediates hypoxia-induced pathological retinal n...
PKCθ-JunB axis via upregulation of VEGFR3 expression mediates hypoxia-induced pathological retinal neovascularization
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Pathological retinal neovascularization is the most common cause of vision loss. PKCθ has been shown to play a role in type 2 diabetes, which is linked to retinal neovascularization. Based on these clues, we have studied the role of PKCθ and its downstream target genes JunB and VEGFR3 in retinal neovascularization using global and tissue-specific k...
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PKCθ-JunB axis via upregulation of VEGFR3 expression mediates hypoxia-induced pathological retinal neovascularization
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7206019
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7206019
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2041-4889
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2041-4889
DOI
10.1038/s41419-020-2522-0