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CCAAT/enhancer binding protein δ is a transcriptional repressor of α-synuclein

CCAAT/enhancer binding protein δ is a transcriptional repressor of α-synuclein

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7206087

CCAAT/enhancer binding protein δ is a transcriptional repressor of α-synuclein

About this item

Full title

CCAAT/enhancer binding protein δ is a transcriptional repressor of α-synuclein

Publisher

London: Nature Publishing Group UK

Journal title

Cell death and differentiation, 2020-02, Vol.27 (2), p.509-524

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

α-Synuclein is the main component of Lewy bodies, the intracellular protein aggregates representing the histological hallmark of Parkinson’s disease. Elevated α-synuclein levels and mutations in SNCA gene are associated with increased risk for Parkinson’s disease. Despite this, little is known about the molecular mechanisms regulating SNCA transcri...

Alternative Titles

Full title

CCAAT/enhancer binding protein δ is a transcriptional repressor of α-synuclein

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7206087

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7206087

Other Identifiers

ISSN

1350-9047

E-ISSN

1476-5403

DOI

10.1038/s41418-019-0368-8

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