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CPAP promotes angiogenesis and metastasis by enhancing STAT3 activity

CPAP promotes angiogenesis and metastasis by enhancing STAT3 activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7206147

CPAP promotes angiogenesis and metastasis by enhancing STAT3 activity

About this item

Full title

CPAP promotes angiogenesis and metastasis by enhancing STAT3 activity

Publisher

London: Nature Publishing Group UK

Journal title

Cell death and differentiation, 2020-04, Vol.27 (4), p.1259-1273

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Centrosomal P4.1-associated protein (CPAP) is overexpressed in hepatocellular carcinoma (HCC) and positively correlated with recurrence and vascular invasion. Here, we found that CPAP plays an important role in HCC malignancies. Functional characterization indicated that CPAP overexpression increases tumor growth, angiogenesis, and metastasis ex vi...

Alternative Titles

Full title

CPAP promotes angiogenesis and metastasis by enhancing STAT3 activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7206147

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7206147

Other Identifiers

ISSN

1350-9047

E-ISSN

1476-5403

DOI

10.1038/s41418-019-0413-7

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