Dual neutralisation of interleukin-17A and interleukin-17F with bimekizumab in patients with active...
Dual neutralisation of interleukin-17A and interleukin-17F with bimekizumab in patients with active ankylosing spondylitis: results from a 48-week phase IIb, randomised, double-blind, placebo-controlled, dose-ranging study
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England: BMJ Publishing Group Ltd and European League Against Rheumatism
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Language
English
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England: BMJ Publishing Group Ltd and European League Against Rheumatism
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ObjectivesBimekizumab selectively neutralises both interleukin (IL)-17A and IL-17F. We report efficacy and safety in a phase IIb dose-ranging study in patients with active ankylosing spondylitis (AS).MethodsAdults with AS (fulfilling modified New York criteria) were randomised 1:1:1:1:1 to bimekizumab 16 mg, 64 mg, 160 mg, 320 mg or placebo every 4...
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Full title
Dual neutralisation of interleukin-17A and interleukin-17F with bimekizumab in patients with active ankylosing spondylitis: results from a 48-week phase IIb, randomised, double-blind, placebo-controlled, dose-ranging study
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7213320
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7213320
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ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2020-216980
