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Virtual Screening and Optimization of Novel mTOR Inhibitors for Radiosensitization of Hepatocellular...

Virtual Screening and Optimization of Novel mTOR Inhibitors for Radiosensitization of Hepatocellular...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7220363

Virtual Screening and Optimization of Novel mTOR Inhibitors for Radiosensitization of Hepatocellular Carcinoma

About this item

Full title

Virtual Screening and Optimization of Novel mTOR Inhibitors for Radiosensitization of Hepatocellular Carcinoma

Publisher

New Zealand: Dove Medical Press Limited

Journal title

Drug design, development and therapy, 2020-01, Vol.14, p.1779-1798

Language

English

Formats

Publication information

Publisher

New Zealand: Dove Medical Press Limited

More information

Scope and Contents

Contents

Radiotherapy has an ameliorative effect on a wide variety of tumors, but hepatocellular carcinoma (HCC) is insensitive to this treatment. Overactivated mammalian target of rapamycin (mTOR) plays an important part in the resistance of HCC to radiotherapy; thus, mTOR inhibitors have potential as novel radiosensitizers to enhance the efficacy of radio...

Alternative Titles

Full title

Virtual Screening and Optimization of Novel mTOR Inhibitors for Radiosensitization of Hepatocellular Carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7220363

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7220363

Other Identifiers

ISSN

1177-8881

E-ISSN

1177-8881

DOI

10.2147/DDDT.S249156

How to access this item