Virtual Screening and Optimization of Novel mTOR Inhibitors for Radiosensitization of Hepatocellular...
Virtual Screening and Optimization of Novel mTOR Inhibitors for Radiosensitization of Hepatocellular Carcinoma
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Publisher
New Zealand: Dove Medical Press Limited
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Language
English
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Publisher
New Zealand: Dove Medical Press Limited
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Contents
Radiotherapy has an ameliorative effect on a wide variety of tumors, but hepatocellular carcinoma (HCC) is insensitive to this treatment. Overactivated mammalian target of rapamycin (mTOR) plays an important part in the resistance of HCC to radiotherapy; thus, mTOR inhibitors have potential as novel radiosensitizers to enhance the efficacy of radio...
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Full title
Virtual Screening and Optimization of Novel mTOR Inhibitors for Radiosensitization of Hepatocellular Carcinoma
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7220363
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7220363
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ISSN
1177-8881
E-ISSN
1177-8881
DOI
10.2147/DDDT.S249156