A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
About this item
Full title
Author / Creator
Slyper, Michal , Porter, Caroline B. M. , Ashenberg, Orr , Waldman, Julia , Drokhlyansky, Eugene , Wakiro, Isaac , Smillie, Christopher , Smith-Rosario, Gabriela , Wu, Jingyi , Dionne, Danielle , Vigneau, Sébastien , Jané-Valbuena, Judit , Tickle, Timothy L. , Napolitano, Sara , Su, Mei-Ju , Patel, Anand G. , Karlstrom, Asa , Gritsch, Simon , Nomura, Masashi , Waghray, Avinash , Gohil, Satyen H. , Tsankov, Alexander M. , Jerby-Arnon, Livnat , Cohen, Ofir , Klughammer, Johanna , Rosen, Yanay , Gould, Joshua , Nguyen, Lan , Hofree, Matan , Tramontozzi, Peter J. , Li, Bo , Wu, Catherine J. , Izar, Benjamin , Haq, Rizwan , Hodi, F. Stephen , Yoon, Charles H. , Hata, Aaron N. , Baker, Suzanne J. , Suvà, Mario L. , Bueno, Raphael , Stover, Elizabeth H. , Clay, Michael R. , Dyer, Michael A. , Collins, Natalie B. , Matulonis, Ursula A. , Wagle, Nikhil , Johnson, Bruce E. , Rotem, Asaf , Rozenblatt-Rosen, Orit and Regev, Aviv
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Single-cell genomics is essential to chart tumor ecosystems. Although single-cell RNA-Seq (scRNA-Seq) profiles RNA from cells dissociated from fresh tumors, single-nucleus RNA-Seq (snRNA-Seq) is needed to profile frozen or hard-to-dissociate tumors. Each requires customization to different tissue and tumor types, posing a barrier to adoption. Here,...
Alternative Titles
Full title
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
Authors, Artists and Contributors
Author / Creator
Porter, Caroline B. M.
Ashenberg, Orr
Waldman, Julia
Drokhlyansky, Eugene
Wakiro, Isaac
Smillie, Christopher
Smith-Rosario, Gabriela
Wu, Jingyi
Dionne, Danielle
Vigneau, Sébastien
Jané-Valbuena, Judit
Tickle, Timothy L.
Napolitano, Sara
Su, Mei-Ju
Patel, Anand G.
Karlstrom, Asa
Gritsch, Simon
Nomura, Masashi
Waghray, Avinash
Gohil, Satyen H.
Tsankov, Alexander M.
Jerby-Arnon, Livnat
Cohen, Ofir
Klughammer, Johanna
Rosen, Yanay
Gould, Joshua
Nguyen, Lan
Hofree, Matan
Tramontozzi, Peter J.
Li, Bo
Wu, Catherine J.
Izar, Benjamin
Haq, Rizwan
Hodi, F. Stephen
Yoon, Charles H.
Hata, Aaron N.
Baker, Suzanne J.
Suvà, Mario L.
Bueno, Raphael
Stover, Elizabeth H.
Clay, Michael R.
Dyer, Michael A.
Collins, Natalie B.
Matulonis, Ursula A.
Wagle, Nikhil
Johnson, Bruce E.
Rotem, Asaf
Rozenblatt-Rosen, Orit
Regev, Aviv
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7220853
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7220853
Other Identifiers
ISSN
1078-8956,1546-170X
E-ISSN
1546-170X
DOI
10.1038/s41591-020-0844-1
