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The early local and systemic Type I interferon responses to ultraviolet B light exposure are cGAS de...

The early local and systemic Type I interferon responses to ultraviolet B light exposure are cGAS de...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7220927

The early local and systemic Type I interferon responses to ultraviolet B light exposure are cGAS dependent

About this item

Full title

The early local and systemic Type I interferon responses to ultraviolet B light exposure are cGAS dependent

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-05, Vol.10 (1), p.7908, Article 7908

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Most systemic lupus erythematosus (SLE) patients are photosensitive and ultraviolet B light (UVB) exposure worsens cutaneous disease and precipitates systemic flares of disease. The pathogenic link between skin disease and systemic exacerbations in SLE remains elusive. In an acute model of UVB-triggered inflammation, we observed that a single UV ex...

Alternative Titles

Full title

The early local and systemic Type I interferon responses to ultraviolet B light exposure are cGAS dependent

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7220927

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7220927

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-64865-w

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