Influence of TYK2 in systemic sclerosis susceptibility: a new locus in the IL-12 pathway
Influence of TYK2 in systemic sclerosis susceptibility: a new locus in the IL-12 pathway
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Author / Creator
Spanish Scleroderma Group , López-Isac, Elena , Campillo-Davo, Diana , Bossini-Castillo, Lara , Guerra, Sandra G , Assassi, Shervin , Simeón, Carmen Pilar , Carreira, Patricia , Ortego-Centeno, Norberto , García de la Peña, Paloma , Beretta, Lorenzo , Santaniello, Alessandro , Bellocchi, Chiara , Lunardi, Claudio , Moroncini, Gianluca , Gabrielli, Armando , Riemekasten, Gabriela , Witte, Torsten , Hunzelmann, Nicolas , Kreuter, Alexander , Distler, Jörg HW , Voskuyl, Alexandre E , de Vries-Bouwstra, Jeska , Herrick, Ariane , Worthington, Jane , Denton, Christopher P , Fonseca, Carmen , Radstake, Timothy RDJ , Mayes, Maureen D and Martín, Javier
Publisher
England: BMJ Publishing Group
Journal title
Language
English
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Publisher
England: BMJ Publishing Group
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Scope and Contents
Contents
ObjectivesTYK2 is a common genetic risk factor for several autoimmune diseases. This gene encodes a protein kinase involved in interleukin 12 (IL-12) pathway, which is a well-known player in the pathogenesis of systemic sclerosis (SSc). Therefore, we aimed to assess the possible role of this locus in SSc.MethodsThis study comprised a total of 7103...
Alternative Titles
Full title
Influence of TYK2 in systemic sclerosis susceptibility: a new locus in the IL-12 pathway
Authors, Artists and Contributors
Author / Creator
López-Isac, Elena
Campillo-Davo, Diana
Bossini-Castillo, Lara
Guerra, Sandra G
Assassi, Shervin
Simeón, Carmen Pilar
Carreira, Patricia
Ortego-Centeno, Norberto
García de la Peña, Paloma
Beretta, Lorenzo
Santaniello, Alessandro
Bellocchi, Chiara
Lunardi, Claudio
Moroncini, Gianluca
Gabrielli, Armando
Riemekasten, Gabriela
Witte, Torsten
Hunzelmann, Nicolas
Kreuter, Alexander
Distler, Jörg HW
Voskuyl, Alexandre E
de Vries-Bouwstra, Jeska
Herrick, Ariane
Worthington, Jane
Denton, Christopher P
Fonseca, Carmen
Radstake, Timothy RDJ
Mayes, Maureen D
Martín, Javier
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7228811
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7228811
Other Identifiers
ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2015-208154
