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RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions

RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7240801

RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions

About this item

Full title

RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2019-12, Vol.20 (12), p.1610-1620

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The initial response to viral infection is anticipatory, with host antiviral restriction factors and pathogen sensors constantly surveying the cell to rapidly mount an antiviral response through the synthesis and downstream activity of interferons. After pathogen clearance, the host’s ability to resolve this antiviral response and return to homeost...

Alternative Titles

Full title

RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7240801

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7240801

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/s41590-019-0527-6

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