Manipulating Sirtuin 3 pathway ameliorates renal damage in experimental diabetes
Manipulating Sirtuin 3 pathway ameliorates renal damage in experimental diabetes
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
More effective treatments for diabetic nephropathy remain a major unmet clinical need. Increased oxidative stress is one of the most important pathological mechanisms that lead to kidney damage and functional impairment induced by diabetes. Sirtuin 3 (SIRT3) is the main mitochondrial deacetylase and critically regulates cellular reactive oxygen spe...
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Full title
Manipulating Sirtuin 3 pathway ameliorates renal damage in experimental diabetes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7242337
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7242337
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-65423-0
