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Guanosine fast onset antidepressant-like effects in the olfactory bulbectomy mice model

Guanosine fast onset antidepressant-like effects in the olfactory bulbectomy mice model

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7242421

Guanosine fast onset antidepressant-like effects in the olfactory bulbectomy mice model

About this item

Full title

Guanosine fast onset antidepressant-like effects in the olfactory bulbectomy mice model

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-05, Vol.10 (1), p.8429, Article 8429

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The treatment of major depressive disorder (MDD) is still a challenge. In the search for novel antidepressants, glutamatergic neuromodulators have been investigated as possible fast-acting antidepressants. Innovative studies suggest that the purine cycle and/or the purinergic signaling can be dysregulated in MDD, and the endogenous nucleoside guano...

Alternative Titles

Full title

Guanosine fast onset antidepressant-like effects in the olfactory bulbectomy mice model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7242421

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7242421

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-65300-w

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