Mitochondrial stress-activated cGAS-STING pathway inhibits thermogenic program and contributes to ov...
Mitochondrial stress-activated cGAS-STING pathway inhibits thermogenic program and contributes to overnutrition-induced obesity in mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Obesity is a global epidemic that is caused by excessive energy intake or inefficient energy expenditure. Brown or beige fat dissipates energy as heat through non-shivering thermogenesis by their high density of mitochondria. However, how the mitochondrial stress-induced signal is coupled to the cellular thermogenic program remains elusive. Here, w...
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Mitochondrial stress-activated cGAS-STING pathway inhibits thermogenic program and contributes to overnutrition-induced obesity in mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7244732
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7244732
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-020-0986-1