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Symphony of epigenetic and metabolic regulation—interaction between the histone methyltransferase EZ...

Symphony of epigenetic and metabolic regulation—interaction between the histone methyltransferase EZ...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7245796

Symphony of epigenetic and metabolic regulation—interaction between the histone methyltransferase EZH2 and metabolism of tumor

About this item

Full title

Symphony of epigenetic and metabolic regulation—interaction between the histone methyltransferase EZH2 and metabolism of tumor

Publisher

Germany: BioMed Central Ltd

Journal title

Clinical epigenetics, 2020-05, Vol.12 (1), p.72-72, Article 72

Language

English

Formats

Publication information

Publisher

Germany: BioMed Central Ltd

More information

Scope and Contents

Contents

Increasing evidence has suggested that epigenetic and metabolic alterations in cancer cells are highly intertwined. As the master epigenetic regulator, enhancer of zeste homolog 2 (EZH2) suppresses gene transcription mainly by catalyzing the trimethylation of histone H3 at lysine 27 (H3K27me3) and exerts highly enzymatic activity in cancer cells. C...

Alternative Titles

Full title

Symphony of epigenetic and metabolic regulation—interaction between the histone methyltransferase EZH2 and metabolism of tumor

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7245796

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7245796

Other Identifiers

ISSN

1868-7075,1868-7083

E-ISSN

1868-7083,1868-7075

DOI

10.1186/s13148-020-00862-0

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