Symphony of epigenetic and metabolic regulation—interaction between the histone methyltransferase EZ...
Symphony of epigenetic and metabolic regulation—interaction between the histone methyltransferase EZH2 and metabolism of tumor
About this item
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Author / Creator
Zhang, Tengrui , Gong, Yueqing , Meng, Hui , Li, Chen and Xue, Lixiang
Publisher
Germany: BioMed Central Ltd
Journal title
Language
English
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Publisher
Germany: BioMed Central Ltd
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Scope and Contents
Contents
Increasing evidence has suggested that epigenetic and metabolic alterations in cancer cells are highly intertwined. As the master epigenetic regulator, enhancer of zeste homolog 2 (EZH2) suppresses gene transcription mainly by catalyzing the trimethylation of histone H3 at lysine 27 (H3K27me3) and exerts highly enzymatic activity in cancer cells. C...
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Full title
Symphony of epigenetic and metabolic regulation—interaction between the histone methyltransferase EZH2 and metabolism of tumor
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Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7245796
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7245796
Other Identifiers
ISSN
1868-7075,1868-7083
E-ISSN
1868-7083,1868-7075
DOI
10.1186/s13148-020-00862-0