Log in to save to my catalogue

Discovery of a new sialic acid binding region that regulates Siglec-7

Discovery of a new sialic acid binding region that regulates Siglec-7

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7250851

Discovery of a new sialic acid binding region that regulates Siglec-7

About this item

Full title

Discovery of a new sialic acid binding region that regulates Siglec-7

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-05, Vol.10 (1), p.8647, Article 8647

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Siglec-7 is a human CD33-like siglec, and is localised predominantly on human natural killer (NK) cells and monocytes. Siglec-7 is considered to function as an immunoreceptor in a sialic acid-dependent manner. However, the underlying mechanisms linking sialic acid-binding and function remain unknown. Here, to gain new insights into the ligand-bindi...

Alternative Titles

Full title

Discovery of a new sialic acid binding region that regulates Siglec-7

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7250851

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7250851

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-64887-4

How to access this item