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Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer

Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7260007

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Transcriptional reactivation of telomerase catalytic subunit (TERT) is a frequent hallmark of cancer, occurring in 90% of human malignancies. However, specific mechanisms driving TERT reactivation remain obscure for many tumor types and in particular gastric cancer (GC), a leading cause of global cancer mortality. Here, through comprehensive genomi...

Alternative Titles

Full title

Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7260007

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7260007

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI126726

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