Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian ra...
Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study
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Full title
Author / Creator
on behalf of the GIST consortium , GIST consortium , Smit, Roelof A. J. , Trompet, Stella , Leong, Aaron , Goodarzi, Mark O. , Postmus, Iris , Warren, Helen , Theusch, Elizabeth , Barnes, Michael R. , Arsenault, Benoit J. , Li, Xiaohui , Feng, QiPing , Chasman, Daniel I. , Cupples, L. Adrienne , Hitman, Graham A. , Krauss, Ronald M. , Psaty, Bruce M. , Rotter, Jerome I. , Cessie, Saskia le , Stein, C. Michael and Jukema, J. Wouter
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
It remains unclear whether the increased risk of new-onset type 2 diabetes (T2D) seen in statin users is due to low LDL-C concentrations, or due to the statin-induced proportional change in LDL-C. In addition, genetic instruments have not been proposed before to examine whether liability to T2D might cause greater proportional statin-induced LDL-C...
Alternative Titles
Full title
Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study
Authors, Artists and Contributors
Author / Creator
GIST consortium
Smit, Roelof A. J.
Trompet, Stella
Leong, Aaron
Goodarzi, Mark O.
Postmus, Iris
Warren, Helen
Theusch, Elizabeth
Barnes, Michael R.
Arsenault, Benoit J.
Li, Xiaohui
Feng, QiPing
Chasman, Daniel I.
Cupples, L. Adrienne
Hitman, Graham A.
Krauss, Ronald M.
Psaty, Bruce M.
Rotter, Jerome I.
Cessie, Saskia le
Stein, C. Michael
Jukema, J. Wouter
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7260089
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7260089
Other Identifiers
ISSN
1470-269X
E-ISSN
1473-1150
DOI
10.1038/s41397-019-0125-x