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Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian ra...

Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian ra...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7260089

Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study

About this item

Full title

Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study

Publisher

London: Nature Publishing Group UK

Journal title

The pharmacogenomics journal, 2020-06, Vol.20 (3), p.462-470

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

It remains unclear whether the increased risk of new-onset type 2 diabetes (T2D) seen in statin users is due to low LDL-C concentrations, or due to the statin-induced proportional change in LDL-C. In addition, genetic instruments have not been proposed before to examine whether liability to T2D might cause greater proportional statin-induced LDL-C...

Alternative Titles

Full title

Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7260089

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7260089

Other Identifiers

ISSN

1470-269X

E-ISSN

1473-1150

DOI

10.1038/s41397-019-0125-x

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