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Structural and catalytic analysis of two diverse uridine phosphorylases in Phytophthora capsici

Structural and catalytic analysis of two diverse uridine phosphorylases in Phytophthora capsici

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7271239

Structural and catalytic analysis of two diverse uridine phosphorylases in Phytophthora capsici

About this item

Full title

Structural and catalytic analysis of two diverse uridine phosphorylases in Phytophthora capsici

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-06, Vol.10 (1), p.9051, Article 9051

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Uridine phosphorylase (UP) is a key enzyme of pyrimidine salvage pathways that enables the recycling of endogenous or exogenous-supplied pyrimidines and plays an important intracellular metabolic role. Here, we biochemically and structurally characterized two evolutionarily divergent uridine phosphorylases, PcUP1 and PcUP2 from the oomycete pathoge...

Alternative Titles

Full title

Structural and catalytic analysis of two diverse uridine phosphorylases in Phytophthora capsici

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7271239

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7271239

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-65935-9

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