High-Capacity Adenoviral Vectors: Expanding the Scope of Gene Therapy
High-Capacity Adenoviral Vectors: Expanding the Scope of Gene Therapy
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
The adaptation of adenoviruses as gene delivery tools has resulted in the development of high-capacity adenoviral vectors (HC-AdVs), also known, helper-dependent or “gutless”. Compared with earlier generations (E1/E3-deleted vectors), HC-AdVs retain relevant features such as genetic stability, remarkable efficacy of in vivo transduction, and produc...
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Full title
High-Capacity Adenoviral Vectors: Expanding the Scope of Gene Therapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7279171
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7279171
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms21103643
