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Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression

Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7281414

Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression

About this item

Full title

Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression

Publisher

Switzerland: MDPI

Journal title

Cancers, 2020-04, Vol.12 (5), p.1088

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

The 3-hydroxy-3-methylglutaryl-CoA synthase 1 (HMGCS1) is a potential regulatory node in the mevalonate pathway that is frequently dysregulated in tumors. This study found that HMGCS1 expression is upregulated in stomach adenocarcinoma samples of patients and tumorspheres of gastric cancer cells. HMGCS1 elevates the expression levels of the pluripo...

Alternative Titles

Full title

Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7281414

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7281414

Other Identifiers

ISSN

2072-6694

E-ISSN

2072-6694

DOI

10.3390/cancers12051088

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