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Afterdepolarizations and abnormal calcium handling in atrial myocytes with modulated SERCA uptake: a...

Afterdepolarizations and abnormal calcium handling in atrial myocytes with modulated SERCA uptake: a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7287332

Afterdepolarizations and abnormal calcium handling in atrial myocytes with modulated SERCA uptake: a sensitivity analysis of calcium handling channels

About this item

Full title

Afterdepolarizations and abnormal calcium handling in atrial myocytes with modulated SERCA uptake: a sensitivity analysis of calcium handling channels

Publisher

England: The Royal Society Publishing

Journal title

Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences, 2020-06, Vol.378 (2173), p.20190557-20190557

Language

English

Formats

Publication information

Publisher

England: The Royal Society Publishing

More information

Scope and Contents

Contents

Delayed afterdepolarizations (DADs) and spontaneous depolarizations (SDs) are typically triggered by spontaneous diastolic Ca
release from the sarcoplasmic reticulum (SR) which is caused by an elevated SR Ca
-ATPase (SERCA) uptake and dysfunctional ryanodine receptors. However, recent studies on the T-box transcription factor gene (TBX5) demo...

Alternative Titles

Full title

Afterdepolarizations and abnormal calcium handling in atrial myocytes with modulated SERCA uptake: a sensitivity analysis of calcium handling channels

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7287332

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7287332

Other Identifiers

ISSN

1364-503X

E-ISSN

1471-2962

DOI

10.1098/rsta.2019.0557

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