Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I
Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I
About this item
Full title
Author / Creator
Yamamoto, Keisuke , Venida, Anthony , Yano, Julian , Biancur, Douglas E. , Kakiuchi, Miwako , Gupta, Suprit , Sohn, Albert S. W. , Mukhopadhyay, Subhadip , Lin, Elaine Y. , Parker, Seth J. , Banh, Robert S. , Paulo, Joao A. , Wen, Kwun Wah , Debnath, Jayanta , Kim, Grace E. , Mancias, Joseph D. , Fearon, Douglas T. , Perera, Rushika M. and Kimmelman, Alec C.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Immune evasion is a major obstacle for cancer treatment. Common mechanisms of evasion include impaired antigen presentation caused by mutations or loss of heterozygosity of the major histocompatibility complex class I (MHC-I), which has been implicated in resistance to immune checkpoint blockade (ICB) therapy
1
–
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. However, in pancrea...
Alternative Titles
Full title
Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I
Authors, Artists and Contributors
Author / Creator
Venida, Anthony
Yano, Julian
Biancur, Douglas E.
Kakiuchi, Miwako
Gupta, Suprit
Sohn, Albert S. W.
Mukhopadhyay, Subhadip
Lin, Elaine Y.
Parker, Seth J.
Banh, Robert S.
Paulo, Joao A.
Wen, Kwun Wah
Debnath, Jayanta
Kim, Grace E.
Mancias, Joseph D.
Fearon, Douglas T.
Perera, Rushika M.
Kimmelman, Alec C.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7296553
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7296553
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2229-5
