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T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibod...

T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibod...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7303014

T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Recent efforts toward an HIV vaccine focus on inducing broadly neutralizing antibodies, but eliciting both neutralizing antibodies (nAbs) and cellular responses may be superior. Here, we immunized macaques with an HIV envelope trimer, either alone to induce nAbs, or together with a heterologous viral vector regimen to elicit nAbs and cellular immun...

Alternative Titles

Full title

T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7303014

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7303014

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/s41591-020-0858-8

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