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Adeno-associated virus-binding antibodies detected in cats living in the Northeastern United States...

Adeno-associated virus-binding antibodies detected in cats living in the Northeastern United States...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7308316

Adeno-associated virus-binding antibodies detected in cats living in the Northeastern United States lack neutralizing activity

About this item

Full title

Adeno-associated virus-binding antibodies detected in cats living in the Northeastern United States lack neutralizing activity

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-06, Vol.10 (1), p.10073-10073, Article 10073

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cats are a critical pre-clinical model for studying adeno-associated virus (AAV) vector-mediated gene therapies. A recent study has described the high prevalence of anti-AAV neutralizing antibodies among domestic cats in Switzerland. However, our knowledge of pre-existing humoral immunity against various AAV serotypes in cats is still limited. Here...

Alternative Titles

Full title

Adeno-associated virus-binding antibodies detected in cats living in the Northeastern United States lack neutralizing activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7308316

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7308316

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-66596-4

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