Growth Differentiation Factor 15 is a potential biomarker of therapeutic response for TK2 deficient...
Growth Differentiation Factor 15 is a potential biomarker of therapeutic response for TK2 deficient myopathy
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Author / Creator
Dominguez-Gonzalez, Cristina , Badosa, Carmen , Madruga-Garrido, Marcos , Martí, Itxaso , Paradas, Carmen , Ortez, Carlos , Diaz-Manera, Jordi , Berardo, Andres , Alonso-Pérez, Jorge , Trifunov, Selena , Cuadras, Daniel , Kalko, Susana G. , Blázquez-Bermejo, Cora , Cámara, Yolanda , Martí, Ramon , Mavillard, Fabiola , Martin, Miguel A. , Montoya, Julio , Ruiz-Pesini, Eduardo , Villarroya, Joan , Montero, Raquel , Villarroya, Francesc , Artuch, Rafael , Hirano, Michio , Nascimento, Andrés and Jimenez-Mallebrera, Cecilia
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
GDF-15 is a biomarker for mitochondrial diseases. We investigated the application of GDF-15 as biomarker of disease severity and response to deoxynucleoside treatment in patients with thymidine kinase 2 (TK2) deficiency and compared it to FGF-21. GDF-15 and FGF-21 were measured in serum from 24 patients with TK2 deficiency treated 1–49 months with...
Alternative Titles
Full title
Growth Differentiation Factor 15 is a potential biomarker of therapeutic response for TK2 deficient myopathy
Authors, Artists and Contributors
Author / Creator
Badosa, Carmen
Madruga-Garrido, Marcos
Martí, Itxaso
Paradas, Carmen
Ortez, Carlos
Diaz-Manera, Jordi
Berardo, Andres
Alonso-Pérez, Jorge
Trifunov, Selena
Cuadras, Daniel
Kalko, Susana G.
Blázquez-Bermejo, Cora
Cámara, Yolanda
Martí, Ramon
Mavillard, Fabiola
Martin, Miguel A.
Montoya, Julio
Ruiz-Pesini, Eduardo
Villarroya, Joan
Montero, Raquel
Villarroya, Francesc
Artuch, Rafael
Hirano, Michio
Nascimento, Andrés
Jimenez-Mallebrera, Cecilia
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7308386
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7308386
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-66940-8
