Phosphorylation of the Anaphase Promoting Complex activator FZR1/CDH1 is required for Meiosis II ent...
Phosphorylation of the Anaphase Promoting Complex activator FZR1/CDH1 is required for Meiosis II entry in mouse male germ cell
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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FZR1/CDH1 is an activator of Anaphase promoting complex/Cyclosome (APC/C), best known for its role as E3 ubiquitin ligase that drives the cell cycle. APC/C activity is regulated by CDK-mediated phosphorylation of FZR1 during mitotic cell cycle. Although the critical role of FZR1 phosphorylation has been shown mainly in yeast and
in vitro
cell...
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Phosphorylation of the Anaphase Promoting Complex activator FZR1/CDH1 is required for Meiosis II entry in mouse male germ cell
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7308413
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7308413
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-67116-0
