RIPK3 blockade attenuates tubulointerstitial fibrosis in a mouse model of diabetic nephropathy
RIPK3 blockade attenuates tubulointerstitial fibrosis in a mouse model of diabetic nephropathy
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Receptor-interacting protein kinase-3 (RIPK3) is a multifunctional regulator of cell death and inflammation. RIPK3 controls cellular signalling through the formation of the domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome, which is recognised to mediate renal fibrogenesis. The role of RIPK3 in diabetic kidney disease (DKD)...
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RIPK3 blockade attenuates tubulointerstitial fibrosis in a mouse model of diabetic nephropathy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7319952
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7319952
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-67054-x
