Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phospha...
Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase
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London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Substrate channeling studies have frequently failed to provide conclusive results due to poor understanding of this subtle phenomenon. We analyzed the mechanism of NADH-channeling from D-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) to L-lactate Dehydrogenase (LDH) using enzymes from different cells. Enzyme kinetics studies showed that LDH activ...
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Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7320145
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7320145
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-67079-2
