Structural basis for plant lutein biosynthesis from α-carotene
Structural basis for plant lutein biosynthesis from α-carotene
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Author / Creator
Niu, Guoqi , Guo, Qi , Wang, Jia , Zhao, Shun , He, Yikun and Liu, Lin
Publisher
Washington: National Academy of Sciences
Journal title
Language
English
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Publisher
Washington: National Academy of Sciences
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Scope and Contents
Contents
Two cytochrome P450 enzymes, CYP97A3 and CYP97C1, catalyze hydroxylations of the β- and ε-rings of α-carotene to produce lutein. Chirality is introduced at the C-3 atom of both rings, and the reactions are both pro-3R–stereospecific. We determined the crystal structures of CYP97A3 in substrate-free and complex forms with a nonnatural substrate and...
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Full title
Structural basis for plant lutein biosynthesis from α-carotene
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7321987
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7321987
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2001806117