Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammat...
Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation
About this item
Full title
Author / Creator
Bhargava, Pavan , Smith, Matthew D. , Mische, Leah , Harrington, Emily , Fitzgerald, Kathryn C. , Martin, Kyle , Kim, Sol , Reyes, Arthur Anthony , Gonzalez-Cardona, Jaime , Volsko, Christina , Tripathi, Ajai , Singh, Sonal , Varanasi, Kesava , Lord, Hannah-Noelle , Meyers, Keya , Taylor, Michelle , Gharagozloo, Marjan , Sotirchos, Elias S. , Nourbakhsh, Bardia , Dutta, Ranjan , Mowry, Ellen M. , Waubant, Emmanuelle and Calabresi, Peter A.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Multiple sclerosis (MS) is an inflammatory demyelinating disorder of the CNS. Bile acids are cholesterol metabolites that can signal through receptors on cells throughout the body, including in the CNS and the immune system. Whether bile acid metabolism is abnormal in MS is unknown. Using global and targeted metabolomic profiling, we identified low...
Alternative Titles
Full title
Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation
Authors, Artists and Contributors
Author / Creator
Smith, Matthew D.
Mische, Leah
Harrington, Emily
Fitzgerald, Kathryn C.
Martin, Kyle
Kim, Sol
Reyes, Arthur Anthony
Gonzalez-Cardona, Jaime
Volsko, Christina
Tripathi, Ajai
Singh, Sonal
Varanasi, Kesava
Lord, Hannah-Noelle
Meyers, Keya
Taylor, Michelle
Gharagozloo, Marjan
Sotirchos, Elias S.
Nourbakhsh, Bardia
Dutta, Ranjan
Mowry, Ellen M.
Waubant, Emmanuelle
Calabresi, Peter A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7324171
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7324171
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI129401
