Exophilin-5 regulates allergic airway inflammation by controlling IL-33–mediated Th2 responses
Exophilin-5 regulates allergic airway inflammation by controlling IL-33–mediated Th2 responses
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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United States: American Society for Clinical Investigation
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Contents
A common variant in the RAB27A gene in adults was recently found to be associated with the fractional exhaled nitric oxide level, a marker of eosinophilic airway inflammation. The small GTPase Rab27 is known to regulate intracellular vesicle traffic, although its role in allergic responses is unclear. We demonstrated that exophilin-5, a Rab27-bindi...
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Full title
Exophilin-5 regulates allergic airway inflammation by controlling IL-33–mediated Th2 responses
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7324203
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7324203
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI127839
