Dual inhibition of PFKFB3 and VEGF normalizes tumor vasculature, reduces lactate production, and imp...
Dual inhibition of PFKFB3 and VEGF normalizes tumor vasculature, reduces lactate production, and improves chemotherapy in glioblastoma: insights from protein expression profiling and MRI
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Author / Creator
Zhang, Junfeng , Xue, Wei , Xu, Kai , Yi, Liang , Guo, Yu , Xie, Tian , Tong, Haipeng , Zhou, Bo , Wang, Shunan , Li, Qing , Liu, Heng , Chen, Xiao , Fang, Jingqin and Zhang, Weiguo
Publisher
Australia: Ivyspring International Publisher Pty Ltd
Journal title
Language
English
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Publication information
Publisher
Australia: Ivyspring International Publisher Pty Ltd
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Scope and Contents
Contents
Tumor vascular normalization (TVN) is emerging to enhance the efficacy of anticancer treatment in many cancers including glioblastoma (GBM). However, a common and severe challenge being currently faced is the transient TVN effect, hampering the sustained administration of anticancer therapy during TVN window. Additionally, the lack of non-contrast...
Alternative Titles
Full title
Dual inhibition of PFKFB3 and VEGF normalizes tumor vasculature, reduces lactate production, and improves chemotherapy in glioblastoma: insights from protein expression profiling and MRI
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7330843
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7330843
Other Identifiers
ISSN
1838-7640
E-ISSN
1838-7640
DOI
10.7150/thno.44427