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Sirt6 deficiency aggravates angiotensin II-induced cholesterol accumulation and injury in podocytes

Sirt6 deficiency aggravates angiotensin II-induced cholesterol accumulation and injury in podocytes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7330847

Sirt6 deficiency aggravates angiotensin II-induced cholesterol accumulation and injury in podocytes

About this item

Full title

Sirt6 deficiency aggravates angiotensin II-induced cholesterol accumulation and injury in podocytes

Publisher

Australia: Ivyspring International Publisher Pty Ltd

Journal title

Theranostics, 2020-01, Vol.10 (16), p.7465-7479

Language

English

Formats

Publication information

Publisher

Australia: Ivyspring International Publisher Pty Ltd

More information

Scope and Contents

Contents

Disturbed renal lipid metabolism, especially cholesterol dysregulation plays a crucial role in the pathogenesis of chronic kidney disease (CKD). We recently reported that angiotensin (Ang) II could induce cholesterol accumulation and injury in podocytes. However, the underlying mechanisms for these alterations remain unknown.
Bioinformatics anal...

Alternative Titles

Full title

Sirt6 deficiency aggravates angiotensin II-induced cholesterol accumulation and injury in podocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7330847

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7330847

Other Identifiers

ISSN

1838-7640

E-ISSN

1838-7640

DOI

10.7150/thno.45003

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