Uncoupling DNA damage from chromatin damage to detoxify doxorubicin
Uncoupling DNA damage from chromatin damage to detoxify doxorubicin
About this item
Full title
Author / Creator
Qiao, Xiaohang , van der Zanden, Sabina Y. , Wander, Dennis P. A. , Borràs, Daniel M. , Song, Ji-Ying , Li, Xiaoyang , van Duikeren, Suzanne , van Gils, Noortje , Rutten, Arjo , van Herwaarden, Tessa , van Tellingen, Olaf , Giacomelli, Elisa , Bellin, Milena , Orlova, Valeria , Tertoolen, Leon G. J. , Gerhardt, Sophie , Akkermans, Jimmy J. , Bakker, Jeroen M. , Zuur, Charlotte L. , Pang, Baoxu , Smits, Anke M. , Mummery, Christine L. , Smith, Linda , Arens, Ramon , Li, Junmin , Overkleeft, Hermen S. and Neefjes, Jacques
Publisher
Washington: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
Washington: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
The anthracycline doxorubicin (Doxo) and its analogs daunorubicin (Daun), epirubicin (Epi), and idarubicin (Ida) have been cornerstones of anticancer therapy for nearly five decades. However, their clinical application is limited by severe side effects, especially dose-dependent irreversible cardiotoxicity. Other detrimental side effects of anthrac...
Alternative Titles
Full title
Uncoupling DNA damage from chromatin damage to detoxify doxorubicin
Authors, Artists and Contributors
Author / Creator
van der Zanden, Sabina Y.
Wander, Dennis P. A.
Borràs, Daniel M.
Song, Ji-Ying
Li, Xiaoyang
van Duikeren, Suzanne
van Gils, Noortje
Rutten, Arjo
van Herwaarden, Tessa
van Tellingen, Olaf
Giacomelli, Elisa
Bellin, Milena
Orlova, Valeria
Tertoolen, Leon G. J.
Gerhardt, Sophie
Akkermans, Jimmy J.
Bakker, Jeroen M.
Zuur, Charlotte L.
Pang, Baoxu
Smits, Anke M.
Mummery, Christine L.
Smith, Linda
Arens, Ramon
Li, Junmin
Overkleeft, Hermen S.
Neefjes, Jacques
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7334570
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7334570
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1922072117
