Functional and transcriptional characterization of complex neuronal co-cultures
Functional and transcriptional characterization of complex neuronal co-cultures
About this item
Full title
Author / Creator
Enright, Heather A. , Lam, Doris , Sebastian, Aimy , Sales, Ana Paula , Cadena, Jose , Hum, Nicholas R. , Osburn, Joanne J. , Peters, Sandra K. G. , Petkus, Bryan , Soscia, David A. , Kulp, Kristen S. , Loots, Gabriela G. , Wheeler, Elizabeth K. , Fischer, Nicholas O. and Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Brain-on-a-chip systems are designed to simulate brain activity using traditional in vitro cell culture on an engineered platform. It is a noninvasive tool to screen new drugs, evaluate toxicants, and elucidate disease mechanisms. However, successful recapitulation of brain function on these systems is dependent on the complexity of the cell cultur...
Alternative Titles
Full title
Functional and transcriptional characterization of complex neuronal co-cultures
Authors, Artists and Contributors
Author / Creator
Lam, Doris
Sebastian, Aimy
Sales, Ana Paula
Cadena, Jose
Hum, Nicholas R.
Osburn, Joanne J.
Peters, Sandra K. G.
Petkus, Bryan
Soscia, David A.
Kulp, Kristen S.
Loots, Gabriela G.
Wheeler, Elizabeth K.
Fischer, Nicholas O.
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7335084
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7335084
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-67691-2
