Anti-integrin αv therapy improves cardiac fibrosis after myocardial infarction by blunting cardiac P...
Anti-integrin αv therapy improves cardiac fibrosis after myocardial infarction by blunting cardiac PW1+ stromal cells
About this item
Full title
Author / Creator
Bouvet, Marion , Claude, Olivier , Roux, Maguelonne , Skelly, Dan , Masurkar, Nihar , Mougenot, Nathalie , Nadaud, Sophie , Blanc, Catherine , Delacroix, Clément , Chardonnet, Solenne , Pionneau, Cédric , Perret, Claire , Yaniz-Galende, Elisa , Rosenthal, Nadia , Trégouët, David-Alexandre , Marazzi, Giovanna , Silvestre, Jean-Sébastien , Sassoon, David and Hulot, Jean-Sébastien
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
There is currently no therapy to limit the development of cardiac fibrosis and consequent heart failure. We have recently shown that cardiac fibrosis post-myocardial infarction (MI) can be regulated by resident cardiac cells with a fibrogenic signature and identified by the expression of PW1 (
Peg3
). Here we identify αV-integrin (CD51) as an...
Alternative Titles
Full title
Anti-integrin αv therapy improves cardiac fibrosis after myocardial infarction by blunting cardiac PW1+ stromal cells
Authors, Artists and Contributors
Author / Creator
Claude, Olivier
Roux, Maguelonne
Skelly, Dan
Masurkar, Nihar
Mougenot, Nathalie
Nadaud, Sophie
Blanc, Catherine
Delacroix, Clément
Chardonnet, Solenne
Pionneau, Cédric
Perret, Claire
Yaniz-Galende, Elisa
Rosenthal, Nadia
Trégouët, David-Alexandre
Marazzi, Giovanna
Silvestre, Jean-Sébastien
Sassoon, David
Hulot, Jean-Sébastien
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7347632
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7347632
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-68223-8
