Computational Drug Repositioning for Chagas Disease Using Protein-Ligand Interaction Profiling
Computational Drug Repositioning for Chagas Disease Using Protein-Ligand Interaction Profiling
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Chagas disease, caused by
(
), affects nearly eight million people worldwide. There are currently only limited treatment options, which cause several side effects and have drug resistance. Thus, there is a great need for a novel, improved Chagas treatment. Bifunctional enzyme dihydrofolate reductase-thymidylate synthase (DHFR-TS) has emerged...
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Full title
Computational Drug Repositioning for Chagas Disease Using Protein-Ligand Interaction Profiling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7348847
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7348847
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms21124270
