RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues
RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues
About this item
Full title
Author / Creator
Yizhak, Keren , Aguet, François , Kim, Jaegil , Hess, Julian M. , Kübler, Kirsten , Grimsby, Jonna , Frazer, Ruslana , Zhang, Hailei , Haradhvala, Nicholas J. , Rosebrock, Daniel , Livitz, Dimitri , Li, Xiao , Arich-Landkof, Eila , Shoresh, Noam , Stewart, Chip , Segrè, Ayellet V. , Branton, Philip A. , Polak, Paz , Ardlie, Kristin G. and Getz, Gad
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
United States: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Somatic cells can accumulate mutations over the course of an individual's lifetime. This generates cells that differ genetically at specific loci within the genome. To explore how this genetic diversity in individuals contributes to disease, Yizhak
et al.
developed a method to detect mutations from RNA sequencing data (see the Perspective by...
Alternative Titles
Full title
RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues
Authors, Artists and Contributors
Author / Creator
Aguet, François
Kim, Jaegil
Hess, Julian M.
Kübler, Kirsten
Grimsby, Jonna
Frazer, Ruslana
Zhang, Hailei
Haradhvala, Nicholas J.
Rosebrock, Daniel
Livitz, Dimitri
Li, Xiao
Arich-Landkof, Eila
Shoresh, Noam
Stewart, Chip
Segrè, Ayellet V.
Branton, Philip A.
Polak, Paz
Ardlie, Kristin G.
Getz, Gad
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7350423
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7350423
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aaw0726
