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Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cel...

Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cel...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7360735

Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cells

About this item

Full title

Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cells

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-07, Vol.10 (1), p.11597-11597, Article 11597

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Inspired by recent proteomic data demonstrating the upregulation of carbon and glycogen metabolism in aging human hematopoietic stem and progenitor cells (HPCs, CD34+ cells), this report addresses whether this is caused by elevated glycolysis of the HPCs on a per cell basis, or by a subpopulation that has become more glycolytic. The average glycoge...

Alternative Titles

Full title

Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7360735

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7360735

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-68396-2

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