Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cel...
Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Inspired by recent proteomic data demonstrating the upregulation of carbon and glycogen metabolism in aging human hematopoietic stem and progenitor cells (HPCs, CD34+ cells), this report addresses whether this is caused by elevated glycolysis of the HPCs on a per cell basis, or by a subpopulation that has become more glycolytic. The average glycoge...
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Full title
Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7360735
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7360735
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-68396-2