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Mesenchymal stromal/stem cells modulate response to experimental sepsis-induced lung injury via regu...

Mesenchymal stromal/stem cells modulate response to experimental sepsis-induced lung injury via regu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7361025

Mesenchymal stromal/stem cells modulate response to experimental sepsis-induced lung injury via regulation of miR-27a-5p in recipient mice

About this item

Full title

Mesenchymal stromal/stem cells modulate response to experimental sepsis-induced lung injury via regulation of miR-27a-5p in recipient mice

Publisher

London: BMJ Publishing Group Ltd and British Thoracic Society

Journal title

Thorax, 2020-07, Vol.75 (7), p.556-567

Language

English

Formats

Publication information

Publisher

London: BMJ Publishing Group Ltd and British Thoracic Society

More information

Scope and Contents

Contents

IntroductionMesenchymal stromal cell (MSC) therapy mitigates lung injury and improves survival in murine models of sepsis. Precise mechanisms of therapeutic benefit remain poorly understood.ObjectivesTo identify host-derived regulatory elements that may contribute to the therapeutic effects of MSCs, we profiled the microRNAome (miRNAome) and transc...

Alternative Titles

Full title

Mesenchymal stromal/stem cells modulate response to experimental sepsis-induced lung injury via regulation of miR-27a-5p in recipient mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7361025

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7361025

Other Identifiers

ISSN

0040-6376

E-ISSN

1468-3296

DOI

10.1136/thoraxjnl-2019-213561

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