Tuberculosis bacillary load, an early marker of disease severity: the utility of tuberculosis Molecu...
Tuberculosis bacillary load, an early marker of disease severity: the utility of tuberculosis Molecular Bacterial Load Assay
About this item
Full title
Author / Creator
Sabiiti, Wilber , Azam, Khalide , Farmer, Eoghan Charles William , Kuchaka, Davis , Mtafya, Bariki , Bowness, Ruth , Oravcova, Katarina , Honeyborne, Isobella , Evangelopoulos, Dimitrios , McHugh, Timothy Daniel , Khosa, Celso , Rachow, Andrea , Heinrich, Norbert , Kampira, Elizabeth , Davies, Geraint , Bhatt, Nilesh , Ntinginya, Elias N , Viegas, Sofia , Jani, Ilesh , Kamdolozi, Mercy , Mdolo, Aaron , Khonga, Margaret , Boeree, Martin J , Phillips, Patrick P J , Sloan, Derek , Hoelscher, Michael , Kibiki, Gibson and Gillespie, Stephen H
Publisher
England: BMJ Publishing Group Ltd and British Thoracic Society
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd and British Thoracic Society
Subjects
More information
Scope and Contents
Contents
In this comparative biomarker study, we analysed 1768 serial sputum samples from 178 patients at 4 sites in Southeast Africa. We show that tuberculosis Molecular Bacterial Load Assay (TB-MBLA) reduces time-to-TB-bacillary-load-result from days/weeks by culture to hours and detects early patient treatment response. By day 14 of treatment, 5% of pati...
Alternative Titles
Full title
Tuberculosis bacillary load, an early marker of disease severity: the utility of tuberculosis Molecular Bacterial Load Assay
Authors, Artists and Contributors
Author / Creator
Azam, Khalide
Farmer, Eoghan Charles William
Kuchaka, Davis
Mtafya, Bariki
Bowness, Ruth
Oravcova, Katarina
Honeyborne, Isobella
Evangelopoulos, Dimitrios
McHugh, Timothy Daniel
Khosa, Celso
Rachow, Andrea
Heinrich, Norbert
Kampira, Elizabeth
Davies, Geraint
Bhatt, Nilesh
Ntinginya, Elias N
Viegas, Sofia
Jani, Ilesh
Kamdolozi, Mercy
Mdolo, Aaron
Khonga, Margaret
Boeree, Martin J
Phillips, Patrick P J
Sloan, Derek
Hoelscher, Michael
Kibiki, Gibson
Gillespie, Stephen H
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7361026
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7361026
Other Identifiers
ISSN
0040-6376
E-ISSN
1468-3296
DOI
10.1136/thoraxjnl-2019-214238
