The discovery of a new antibody for BRIL-fused GPCR structure determination
The discovery of a new antibody for BRIL-fused GPCR structure determination
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
G-protein-coupled receptors (GPCRs)—the largest family of cell-surface membrane proteins—mediate the intracellular signal transduction of many external ligands. Thus, GPCRs have become important drug targets. X-ray crystal structures of GPCRs are very useful for structure-based drug design (SBDD). Herein, we produced a new antibody (SRP2070) target...
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Full title
The discovery of a new antibody for BRIL-fused GPCR structure determination
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7363855
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7363855
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-68355-x
