Nucleosome binding by the pioneer transcription factor OCT4
Nucleosome binding by the pioneer transcription factor OCT4
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Transcription factor binding to genomic DNA is generally prevented by nucleosome formation, in which the DNA is tightly wrapped around the histone octamer. In contrast, pioneer transcription factors efficiently bind their target DNA sequences within the nucleosome. OCT4 has been identified as a pioneer transcription factor required for stem cell pl...
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Full title
Nucleosome binding by the pioneer transcription factor OCT4
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7367260
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7367260
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-68850-1
