The HERC1 ubiquitin ligase regulates presynaptic membrane dynamics of central synapses
The HERC1 ubiquitin ligase regulates presynaptic membrane dynamics of central synapses
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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HERC1 is a ubiquitin ligase protein, which, when mutated, induces several malformations and intellectual disability in humans. The animal model of HERC1 mutation is the mouse
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characterized by: (1) overproduction of the protein; (2) cerebellar Purkinje cells death by autophagy; (3) dysregulation of autophagy in spinal cord motor ne...
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Full title
The HERC1 ubiquitin ligase regulates presynaptic membrane dynamics of central synapses
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7374096
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7374096
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-68970-8
