Mitomycin C treatment improves pancreatic islet graft longevity in intraportal islet transplantation...
Mitomycin C treatment improves pancreatic islet graft longevity in intraportal islet transplantation by suppressing proinflammatory response
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The in vitro culture period prior to cell transplantation (i.e. pancreatic islet transplantation) enables cell modification and is thus advantageous. However, the islet preconditioning method has not been fully explored. Here we present a simple approach for islet preconditioning that uses the antibiotic mitomycin C (MMC), which has antitumor activ...
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Full title
Mitomycin C treatment improves pancreatic islet graft longevity in intraportal islet transplantation by suppressing proinflammatory response
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7374693
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7374693
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-69009-8
