Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes
Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes
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Author / Creator
PERL Study Group , Doria, Alessandro , Galecki, Andrzej T , Spino, Cathie , Pop-Busui, Rodica , Cherney, David Z , Lingvay, Ildiko , Parsa, Afshin , Rossing, Peter , Sigal, Ronald J , Afkarian, Maryam , Aronson, Ronnie , Caramori, M. Luiza , Crandall, Jill P , de Boer, Ian H , Elliott, Thomas G , Goldfine, Allison B , Haw, J. Sonya , Hirsch, Irl B , Karger, Amy B , Maahs, David M , McGill, Janet B , Molitch, Mark E , Perkins, Bruce A , Polsky, Sarit , Pragnell, Marlon , Robiner, William N , Rosas, Sylvia E , Senior, Peter , Tuttle, Katherine R , Umpierrez, Guillermo E , Wallia, Amisha , Weinstock, Ruth S , Wu, Chunyi and Mauer, Michael
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
In a double-blind trial, patients with type 1 diabetes and early-to-moderate diabetic kidney disease were randomly assigned to receive allopurinol, which may slow the decline in the glomerular filtration rate, or placebo. There were no clinically meaningful benefits of serum urate reduction on kidney outcomes with allopurinol therapy.
Alternative Titles
Full title
Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes
Authors, Artists and Contributors
Author / Creator
Doria, Alessandro
Galecki, Andrzej T
Spino, Cathie
Pop-Busui, Rodica
Cherney, David Z
Lingvay, Ildiko
Parsa, Afshin
Rossing, Peter
Sigal, Ronald J
Afkarian, Maryam
Aronson, Ronnie
Caramori, M. Luiza
Crandall, Jill P
de Boer, Ian H
Elliott, Thomas G
Goldfine, Allison B
Haw, J. Sonya
Hirsch, Irl B
Karger, Amy B
Maahs, David M
McGill, Janet B
Molitch, Mark E
Perkins, Bruce A
Polsky, Sarit
Pragnell, Marlon
Robiner, William N
Rosas, Sylvia E
Senior, Peter
Tuttle, Katherine R
Umpierrez, Guillermo E
Wallia, Amisha
Weinstock, Ruth S
Wu, Chunyi
Mauer, Michael
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7375708
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7375708
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1916624
