An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
About this item
Full title
Author / Creator
Jackson, Lisa A , Anderson, Evan J , Rouphael, Nadine G , Roberts, Paul C , Makhene, Mamodikoe , Coler, Rhea N , McCullough, Michele P , Chappell, James D , Denison, Mark R , Stevens, Laura J , Pruijssers, Andrea J , McDermott, Adrian , Flach, Britta , Doria-Rose, Nicole A , Corbett, Kizzmekia S , Morabito, Kaitlyn M , O’Dell, Sijy , Schmidt, Stephen D , Swanson, Phillip A , Padilla, Marcelino , Mascola, John R , Neuzil, Kathleen M , Bennett, Hamilton , Sun, Wellington , Peters, Etza , Makowski, Mat , Albert, Jim , Cross, Kaitlyn , Buchanan, Wendy , Pikaart-Tautges, Rhonda , Ledgerwood, Julie E , Graham, Barney S , Beigel, John H and mRNA-1273 Study Group
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Two inoculations with a new SARS-CoV-2 mRNA-based vaccine that encodes a protein in the coronavirus spike elicited high titers of virus-neutralizing antibody in healthy adult volunteers. Virus-specific T-cell responses were also elicited. Interim findings indicated that a dose of 100 μg per injection maximized immune response and minimized the reac...
Alternative Titles
Full title
An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
Authors, Artists and Contributors
Author / Creator
Anderson, Evan J
Rouphael, Nadine G
Roberts, Paul C
Makhene, Mamodikoe
Coler, Rhea N
McCullough, Michele P
Chappell, James D
Denison, Mark R
Stevens, Laura J
Pruijssers, Andrea J
McDermott, Adrian
Flach, Britta
Doria-Rose, Nicole A
Corbett, Kizzmekia S
Morabito, Kaitlyn M
O’Dell, Sijy
Schmidt, Stephen D
Swanson, Phillip A
Padilla, Marcelino
Mascola, John R
Neuzil, Kathleen M
Bennett, Hamilton
Sun, Wellington
Peters, Etza
Makowski, Mat
Albert, Jim
Cross, Kaitlyn
Buchanan, Wendy
Pikaart-Tautges, Rhonda
Ledgerwood, Julie E
Graham, Barney S
Beigel, John H
mRNA-1273 Study Group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7377258
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7377258
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2022483
