IL-21 Stimulates the expression and activation of cell cycle regulators and promotes cell proliferat...
IL-21 Stimulates the expression and activation of cell cycle regulators and promotes cell proliferation in EBV-positive diffuse large B cell lymphoma
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Author / Creator
Wang, Yuxuan , Wang, Chengcheng , Cai, Xiyunyi , Mou, Chang , Cui, Xueting , Zhang, Yingying , Ge, Feng , Dong, Hao , Hao, Yuanyuan , Cai, Lei , Wu, Shuting , Feng, Chenjie , Chen, Jiamin , Li, Jianyong , Xu, Wei , Fan, Lei , Xie, Weijia , Tong, Yue , Gu, Harvest Feng and Wu, Liang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The clinical features of EBV-positive diffuse large B cell lymphoma (DLBCL) indicate a poorer prognosis than EBV-negative DLBCL. Currently, there is no efficacious drug for EBV-positive DLBCL. The cytokine interleukin-21 (IL-21) has been reported to be pro-apoptotic in DLBCL cell lines and is being explored as a new therapeutic strategy for this ty...
Alternative Titles
Full title
IL-21 Stimulates the expression and activation of cell cycle regulators and promotes cell proliferation in EBV-positive diffuse large B cell lymphoma
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7378064
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7378064
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-69227-0
