Pembrolizumab for management of patients with NSCLC and brain metastases: long-term results and biom...
Pembrolizumab for management of patients with NSCLC and brain metastases: long-term results and biomarker analysis from a non-randomised, open-label, phase 2 trial
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Author / Creator
Goldberg, Sarah B, MD , Schalper, Kurt A, MD , Gettinger, Scott N, Prof , Mahajan, Amit, MD , Herbst, Roy S, Prof , Chiang, Anne C, MD , Lilenbaum, Rogerio, Prof , Wilson, Frederick H, MD , Omay, Sacit Bulent, MD , Yu, James B, Prof , Jilaveanu, Lucia, PhD , Tran, Thuy, MD , Pavlik, Kira, MPH , Rowen, Elin, MSN , Gerrish, Heather, BSN , Komlo, Annette, MBA , Gupta, Richa, BS , Wyatt, Hailey, BS , Ribeiro, Matthew, BS , Kluger, Yuval, Prof , Zhou, Geyu, BSc , Wei, Wei, PhD , Chiang, Veronica L, Prof and Kluger, Harriet M, Prof
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Contents
SummaryBackgroundWe did a phase 2 trial of pembrolizumab in patients with non-small-cell lung cancer (NSCLC) or melanoma with untreated brain metastases to determine the activity of PD-1 blockade in the CNS. Interim results were previously published, and we now report an updated analysis of the full NSCLC cohort. MethodsThis was an open-label, phas...
Alternative Titles
Full title
Pembrolizumab for management of patients with NSCLC and brain metastases: long-term results and biomarker analysis from a non-randomised, open-label, phase 2 trial
Authors, Artists and Contributors
Author / Creator
Schalper, Kurt A, MD
Gettinger, Scott N, Prof
Mahajan, Amit, MD
Herbst, Roy S, Prof
Chiang, Anne C, MD
Lilenbaum, Rogerio, Prof
Wilson, Frederick H, MD
Omay, Sacit Bulent, MD
Yu, James B, Prof
Jilaveanu, Lucia, PhD
Tran, Thuy, MD
Pavlik, Kira, MPH
Rowen, Elin, MSN
Gerrish, Heather, BSN
Komlo, Annette, MBA
Gupta, Richa, BS
Wyatt, Hailey, BS
Ribeiro, Matthew, BS
Kluger, Yuval, Prof
Zhou, Geyu, BSc
Wei, Wei, PhD
Chiang, Veronica L, Prof
Kluger, Harriet M, Prof
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7380514
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7380514
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(20)30111-X
