L-type Ca2+ channel blockers promote vascular remodeling through activation of STIM proteins
L-type Ca2+ channel blockers promote vascular remodeling through activation of STIM proteins
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Publisher
Washington: National Academy of Sciences
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Language
English
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Publisher
Washington: National Academy of Sciences
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Scope and Contents
Contents
Voltage-gated L-type Ca2+ channel (Cav1.2) blockers (LCCBs) are major drugs for treating hypertension, the preeminent risk factor for heart failure. Vascular smooth muscle cell (VSMC) remodeling is a pathological hallmark of chronic hypertension. VSMC remodeling is characterized by molecular rewiring of the cellular Ca2+ signaling machinery, includ...
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Full title
L-type Ca2+ channel blockers promote vascular remodeling through activation of STIM proteins
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7382247
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7382247
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.2007598117
